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Translating Genetics Into Clinical Knowledge

Video Education on Hereditary Breast and Ovarian Cancer (HBOC) for Physicians: an Interventional Study

Krishnamachari et al. · Journal of Cancer Education · 2017 · DOI: 10.1007/s13187-017-1233-4
136Physicians completed the study
69 / 67Intervention / control group
11,114Physicians invited
2017Publication year

Explore the results

Video educationControl

Percentages represent correct responses for individual survey questions. These are not a composite knowledge score.

Study design and methods

Design

  • Physicians were invited to participate in an online educational study.
  • The intervention group was offered web-based training before completing the knowledge survey.
  • The control group completed the survey before receiving the training.

Analysis

  • Chi-square tests were used for categorical outcomes.
  • t-tests were used for continuous outcomes.
  • Logistic regression estimated adjusted odds ratios and 95% confidence intervals.
  • Analyses were conducted using SAS 9.3.

Limitations reported by the authors

  • No baseline knowledge survey was administered, limiting assessment of change from baseline.
  • The sample was small, with low participation relative to the number invited.
  • Selection bias is possible because participants may have had greater interest in genetics.
  • Compliance with viewing the video was not monitored.

What the findings do and do not establish

The results support an association between the educational intervention and higher correct-response rates on several knowledge questions. They do not establish long-term retention, changes in clinical practice, or improved patient outcomes.